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While every effort has been made to make sure this electronic syllabus is error-free, it is not official.
The definitive source of course information remains the original (paper) syllabus distributed in class.


Course web site: http://www.lycoming.edu/~newman/courses/44405


Spring 2005       Chemistry 444              Lycoming College

Syllabus

Bio444/Chem444  Biochemistry Spring 2005

 

Instructor: Jeffrey D. Newman

Room: Heim 110

Phone: 570-321-4386

email: newman@lycoming.edu

office hours: T 10:00-11:00 PM

            F 3:30-4:30 PM

Instructor: Chriss McDonald

Room:  Heim 233

Phone:  570-321-4186

email mcdonald@lycoming.edu

office hours:  I'm usually around

 

Lecture meets MWF 2:00 2:50 in Heim G-09

Lab meets Thursday  8:45 -11:35 in Heim 106

Course web site: http://www.lycoming.edu/~newman/courses/44405

Text: Nelson & Cox, Principles of Biochemistry, 4th Ed, 2005, Freeman Publishers.

 

Catalog Description of Course: Emphasis is given to the metabolism of carbohydrates, lipids, amino acids, proteins, and nucleic acids; integration of metabolism; and biochemical control mechanisms, including allosteric control, induction, repression, signal transduction as well as the various types of inhibitive control mechanisms.

 

Grades will be determined based on the following assessments:

 

                        Exams                                                            4 x 100 pts = 400 pts

                        Phosphatase Lab Report                                                   100 pts

Lipid Analysis Lab Report                                                  100 pts

Integrated Informatics Project                                            100 pts

                        Problem Sets, Quizzes                               4 x  25 pts = 100 pts

                        Total possible                                                                       800 pts

                                   

 

B+ = 86.7 - 89.9%

C+ = 76.7 79.9%

D+ = 66.7 - 69.9%

 

A = 93.3 100%

B = 83.3 86.6%

C = 73.3 76.6%

D = 63.3 66.6%

F= below 60%

A- = 90.0 93.2%

B- = 80.0 83.2%

C- = 70.0 73.2%

D- = 60.0 63.2%

 

 

Attendance policy: Attendance of all lectures and laboratories is expected.  Absences will be noted by the instructor, and if excessive (more than 1 lab or 5 lectures), may result in a reduction of the course grade. Absences and participation will be used to determine borderline (within 0.5%) grades. Documentation (note from school nurse, physician, documentation of job interview, etc.) for excused absences must be provided to the instructor as soon as possible.

 

 


 

Tentative Schedule

 


 

 

Lecture Topics (chapter)

Lab Activities

Week 1
1/10 1/14

Introduction, Background Review (1,2)

pre-test, intro to online resources

(computer lab)

Week 2

1/17 1/21

Protein Structure (3,4)

Quiz 1 (1/21)

Protein structure and sequence analysis with Chime/Protein Explorer.

(computer lab)

Week 3

1/24 1/28

Protein Function (5)

Exam 1 (1/28)

Begin integrated informatics project (computer lab)

Week 4

1/31 2/4

Enzymes (6)

Measurement of phosphatase activity

Week 5

2/7 2/11

Bioenergetics (13)

Quiz 2 (2/11)

Phosphatase kinetic analysis

Week 6

2/14 2/18

Lipids & Membranes (10, 11)

IIP bibliography due (2/18)

Phosphatase purification Part 1

Week 7

2/21 2/25

Signal Transduction (12)

Exam 2 (2/25?)

Phosphatase purification Part 2

Week 8

3/7 3/11

Carbohydrates & their metabolism (7, 14,15)

IIP Sequence Analysis and Structure Views due (3/11)

Purification of a 6xHis-tagged protein

Week 9

3/14 3/18

Respiration (16, 19)

Phosphatase Lab report due (3/18)

SDS-PAGE analysis of protein fractions

Week 10

3/21 3/25

 

Photosynthesis (19, 20)
Quiz 3 (3/25)

Enzyme Evolution (computer lab)

Week 11

3/28 4/1

Lipid Metabolism  (17, 21) Exam 3 (4/1)

GC/MS analysis of membrane lipids

Week 12

4/4 4/8

Amino Acid Metab. (18, 22)

IIP Analytical Text due (4/8)

GC/MS analysis of membrane lipids

Week 13+

4/11 4/15

Nucleotide Metabolism, (22)

Lipid Analysis Lab report due (4/15)

Analysis of Purine auxotrophs

Week 14

4/18 4/22

Integration of Metabolism (23)

Analysis of Purine auxotrophs

 


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Last updated January 7, 2005.
The URL for this page is http://www.lycoming.edu/chem/spring2005/444syl.htm